Cisplatin livertox

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August undefined, 2024

WebMar 30, 2024 · LiverTox®provides up-to-date, unbiased and easily accessed information on the diagnosis, cause, frequency, clinical patterns and management of liver injury … WebJun 3, 2024 · LiverTox has two major components: 1) an introduction and overview of drug-induced liver injury that includes discussions of clinical patterns, diagnostic criteria, and …

LiverTox: A Website on Drug-Induced Liver Injury

Cisplatin is a chemotherapy medication used to treat a number of cancers. These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors and neuroblastoma. It is given by injection into a vein. Common side effects include bone marrow suppression, hearing problems, incl… WebJul 1, 2024 · LIVERTOX is a freely available website that provides up-to-date, comprehensive and unbiased information about drug induced liver injury caused by prescription and nonprescription drugs, herbal products … ctms library

Introduction - LiverTox - NCBI Bookshelf

WebMar 10, 2015 · The platinum-containing antineoplastic agents [cisplatin, carboplatin, oxaliplatin], which are referred to as platinum coordination complexes. These antineoplastic drugs are usually classified as … WebCisplatin is the prototype platinum coordination complex classified as an alkylating agent and used intravenously in the treatment of several forms of cancer. Cisplatin has been … WebDec 20, 2024 · The interrelationship between the liver and molecularly targeted agents used for cancer therapy are discussed elsewhere, as is hepatotoxicity associated with checkpoint inhibitor immunotherapy, as used for advanced melanoma and other solid tumors. earthquake safety poster

Cisplatin livertox

Cisplatin (Cisplatin Injection): Uses, Dosage, Side Effects ... - RxList

WebPeginterferon alfa-2a is available as a fixed dose injector (tradename Pegasys) used for the treatment of chronic Hepatitis C. Approved in 2002 by the FDA, Pegasys is indicated for the treatment of HCV with Ribavirin or …

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WebSep 15, 2024 · Cisplatin Injection (cisplatin injection (cisplatin (cisplatin injection) injection) ) is a sterile aqueous solution, available in 50, 100 and 200 mL multiple dose … WebMaterials. Cisplatin (Cisplatyl 50 mg, Laboratoire Roger Bellon) was a generous gift from NCI drug store. Silymarin was purchased from Aldrich Chemical Co. The required dose was dissolved in 0.2 ml of propylene glycol in saline 75/25 (v/v) (Mereish et al ., 1991). Experimental design. Cisplatin treatment protocol used in this

WebJun 23, 2024 · Durvalumab is a human monoclonal antibody to programmed cell death ligand 1 (PD-L1), which acts as a checkpoint inhibitor and is used in the immunotherapy of several forms of advanced … WebNov 20, 2024 · Drug induced liver injury is an uncommon but important and challenging form of liver disease. When evaluating a patient with new-onset liver disease, drugs, including prescription drugs, over-the-counter preparations, dietary supplements, vitamins and herbal medications, must always be considered as a possible cause. Indeed, the possibility …

WebMay 18, 2024 · Cisplatin (cis-diamminedichloroplatinum; CP) is an effective alkylating and antineoplastic agent that is widely used in the treatment of solid tumors. 1 The liver is a key organ in the metabolism and detoxification of endobiotics and xenobiotics. 2 CP is accumulated in liver cells, leading to hepatotoxicity. WebJan 1, 2013 · LiverTox has three major components: (1) introductory sections that describe DILI, including the course, diagnosis, clinical phenotypes of injury, immunological …

WebThe DILIrank dataset consists of 1,036 FDA-approved drugs that are divided into four classes according to their potential for causing drug-induced liver injury (DILI). The DILI classification is ...

WebMar 9, 2024 · A typical dosing regimen is 30 minute infusions of 1.0 to 1.2 g/m 2 on days 1, 8 and 15 of each 28 day cycle of chemotherapy. Common side effects include bone marrow suppression, fatigue, diarrhea, nausea, … ctms login ontarioWebMay 7, 2024 · Corticosteroids - LiverTox - NCBI Bookshelf The corticosteroids are a group of chemically related natural hormones and synthetic agents that resemble the human adrenal hormone cortisol and have potent antiinflammatory and immunosuppressive properties and are widely used in medicine. earthquake safety tips flyerWebFeb 2, 2024 · Floxuridine - LiverTox - NCBI Bookshelf Floxuridine (FUDR) is a pyrimidine analogue used as an antineoplastic agent, usually as a continuous hepatic arterial infusion to treat hepatic metastases from … ctms manualWebCisplatin is the prototype platinum coordination complex classified as an alkylating agent and used intravenously in the treatment of several forms of cancer. Cisplatin has been … earthquake safety straps for furnitureWebLiverTox: Clinical and Research Information on Drug-Induced Liver Injury. 2012 In vitro phase II comparison of the cytotoxicity of a novel platinum analog, nedaplatin (254-S), with that of cisplatin and carboplatin against fresh, human ovarian cancers. [Cancer Chemother Pharmacol. 1997] earthquake safety video for kidsWebApr 5, 2024 · LiverTox® provides up-to-date, unbiased and easily accessed information on the diagnosis, cause, frequency, clinical patterns and management of liver injury … ctm smash repairWebwww.ncbi.nlm.nih.gov earthquake safety water heater strapping