WebThe MTX analogues were obtained by reaction of 4-amino-4-deoxy-N10-methylpteroic acid (mAPA) and N omega-Boc-alpha,omega-diaminoalkanoic acids in the presence of diethyl phosphorocyanidate, followed by deprotection with trifluoroacetic acid (TFA) or by reaction of p-nitrophenyl-mAPA and N omega-Boc-alpha,omega-diaminoalkanoic acids and ... WebDec 15, 2006 · Diethyl phosphorocyanidate (DEPC) can be efficiently used for the synthesis of α-amino nitriles from carbonyl compounds and amines. The reaction may be …

Diethyl cyanophosphonate C5H10NO3P - PubChem

WebJan 1, 1979 · Diethyl phosphorocyanidate (DEPC) can be efficiently used for the synthesis of α-amino nitriles from carbonyl compounds and amines. The reaction may be … WebReaction of 1,4-benzoquinones (1a,b) with diethyl phosphorocyanidate and lithium cyanide was found to give the monocyanophosphates (2a,b).When catalysed by BF 3 ·OEt 2, the cyanophosphates (2a,b) reacted with aromatic and heteroaromatic compounds (indole, thiophene, and furan derivatives) to give 3-aryl-4-hydroxybenzonitriles.Under the … fire nfirs

New methods and reagents in organic synthesis, 23, diethyl ...

WebShop a large selection of Organic phosphonic acids and derivatives products and learn more about Diethyl Cyanophosphonate 95.0 %, TCI America. 5G. Fisher Scientific ; Fisher Healthcare ; Fisher Science Education ... diethyl cyanophosphonate,diethyl phosphorocyanidate,diethylphosphorocyanidate,diethylcyanophosphate,diethyl … WebApr 15, 2001 · Alternate Names:diethyl cyanophosphonate; diethylphosphoryl cyanide; diethoxyphosphoryl cyanide; diethyl cyanophosphate; DEPC. Physical Data:bp 93–96 … WebMar 4, 1999 · Use of diethyl phosphorocyanidate for the peptide bond formations gave the linear heptapeptide in 54% yield. Cyclization was achieved in high yields utilizing TBTU ( 2 ), BOP-C1 ( 3 ), PyBroP ( 4 ), and HOAt ( 5 ), resulting in 50−65% yields of phakellistatin 2 ( 1 ) depending on the method employed. fire nfirs report