WebThe invention relates to the use of an anti-P-selectin antibody or binding fragment thereof, suitably crizanlizumab or a binding fragment thereof in the treatment of myelofibrosis (MF). The invention also relates to a pharmaceutical combination comprising a) an anti-P-Selectin antibody and b) at least one further therapeutic agent, preferably ruxolitinib or a … WebNov 5, 2024 · Methods: For both mAbs, we assessed: P-selectin affinity (surface plasmon resonance [SPR]/Biacore assay); inhibition of adhesion of P-selectin-expressing cells to P …
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WebP-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins … WebP-Selectin Antibody (CTB201) is an IgG 1 κ mouse monoclonal P-Selectin antibody (also designated CD62 antibody, SELP antibody, selectin P antibody) suitable for the detection of the P-Selectin protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM. P-Selectin Antibody (CTB201) is available as both the non-conjugated anti-P-Selectin … doacs and gastric bypass
CD62P/P-Selectin (E8Q1W) XP® Rabbit mAb - Cell Signaling …
WebCD62P is a 140 kD type I transmembrane glycoprotein also known as P-selectin, platelet activation-dependent granule membrane protein (PADGEM), and GMP-140. It is expressed on activated platelets, megakaryocytes, and endothelial cells. CD62P is primarily stored in secretory α-granules in platelets and Weibel-Palade bodies in endothelial cells ... WebP-Selectin (CD62P), previously termed PADGEM or GMP-140, is a single chain glycoprotein of 140 kDa expressed in platelets and endothelial cells. In platelets, P-selectin is stored in … WebWestern Blot analysis of P-Selectin (CD62P) in various cell lines using a P-Selectin (CD62P) Polyclonal antibody ( Product # PA5-120169) at a dilution of 1:1,000. 25 µg of lysate or protein were loaded into each lane. A blocking buffer of 3% nonfat dry milk in TBST was used. An HRP conjugated Goat Anti-Rabbit IgG (H+L) secondary antibody was ... create own t-shirt logo