Tīmeklis2016. gada 17. apr. · Generic Name Ravulizumab DrugBank Accession Number DB11580 Background. Ravulizumab is a potent and selective complement 5 (C5) inhibitor. It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells. 4 Ravulizumab was engineered from eculizumab, … TīmeklisRavulizumab, sold under the brand name Ultomiris, is a humanized monoclonal antibody complement inhibitor medication designed for the treatment of paroxysmal …
EU/3/20/2272 European Medicines Agency
TīmeklisRavulizumab (Ultomiris®) for the treatment of patients with a body weight of 10 kg or above with atypical haemolytic uremic syndrome who are complement inhibitor treatment-naive or have received eculizumab for at least 3 months and have evidence of response to eculizumab (May 2024) Recommended with restrictions. Tīmeklis2024. gada 12. dec. · Synagis 100 mg/1ml solution for injection. Active Ingredient: palivizumab. Company: AstraZeneca UK Limited See contact details. ATC code: … hilton resorts new jersey
Swiss Summary of the Risk Management Plan for Ultomiris® (Ravulizumab)
TīmeklisPlease see SmPC for Ravulizumab, including information regarding serious meningococcal infection 4 TREATMENT DISCONTINUATION1 Treatment discontinuation for PNH: Closely monitor patients with PNH who discontinue ravulizumab for signs and symptoms of haemolysis and other reactions for at least … Tīmeklisdose of ravulizumab. Dose Adjustment Reference ID: 4796130 • For lactate dehydrogenase (LDH) levels greater than 2 × the upper limit of normal (ULN), adjust the dosing regimen to 1,080 mg every three days. • In the event of a dose increase, monitor LDH twice weekly for at least 4 weeks. Tīmeklis2024. gada 21. dec. · Ultomiris (ravulizumab), the first and only long-acting C5 complement inhibitor, offers immediate, complete, and sustained complement inhibition. The medication works by inhibiting the C5 protein in the terminal complement cascade, a part of the body’s immune system. ... (SmPC) for current product information. I have … hilton resorts timeshare policy